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2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms.

2-Chlorodeoxyadenosine (2-CDA) is an adenosine deaminase resistant analogue of deoxyadenosine which has shown clinical activity in human hematologic neoplasms. The exact mode of action of this drug remains the subject of investigation. We applied the Differential Staining Cytotoxicity (DiSC) assay t...

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Detalles Bibliográficos
Autores principales: Nagourney, R. A., Evans, S. S., Messenger, J. C., Su, Y. Z., Weisenthal, L. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968239/
https://www.ncbi.nlm.nih.gov/pubmed/8094002