Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line.

We have studied the genetic alterations acquired during selection of a cloned human leukaemic cell line (CEM/VP-1) that is 15-fold more resistant to the anticancer topoisomerase II-inhibitor etoposide than parental CCRF-CEM cells. CEM/VP-1 cells exhibit an 'atypical MDR' phenotype: cross r...

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Detalles Bibliográficos
Autores principales: Patel, S., Fisher, L. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968246/
https://www.ncbi.nlm.nih.gov/pubmed/8382508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968246/
https://www.ncbi.nlm.nih.gov/pubmed/8382508

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