Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure.

Effects of angiotensin II (AT-II)-induced hypertension on the distribution of macromolecules to Walker carcinoma and to bone marrow of SMANCS [poly(styrene-co-maleic-acid)-neocarzinostatin conjugate] were investigated in rats. AT-II-induced hypertension from about 100 to 150 mmHg significantly incre...

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Detalles Bibliográficos
Autores principales: Li, C. J., Miyamoto, Y., Kojima, Y., Maeda, H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968457/
https://www.ncbi.nlm.nih.gov/pubmed/8494731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968457/
https://www.ncbi.nlm.nih.gov/pubmed/8494731

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