Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.

Loss of heterozygosity (LOH) in tumour cells is generally accepted as 'exposing' recessive cancer genes. The short arm of chromosome 11 shows consistent LOH in Wilms' tumours along its entire length. Occasionally, however, only the 11p13 and/or the 11p15 regions are involved. Deletion...

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Detalles Bibliográficos
Autores principales: Cowell, J. K., Groves, N., Baird, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968481/
https://www.ncbi.nlm.nih.gov/pubmed/8390282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968481/
https://www.ncbi.nlm.nih.gov/pubmed/8390282

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