Differential modulation of doxorubicin toxicity to multidrug and intrinsically drug resistant cell lines by anti-oestrogens and their major metabolites.

The ability of the anti-oestrogens tamoxifen, toremifene and their 4-hydroxy and N-desmethyl metabolites to modify doxorubicin (dox) toxicity to intrinsically resistant and multidrug resistant cell lines was compared, using human breast and lung cancer, and Chinese hamster ovary cell lines. The anti...

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Detalles Bibliográficos
Autores principales: Kirk, J., Houlbrook, S., Stuart, N. S., Stratford, I. J., Harris, A. L., Carmichael, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968530/
https://www.ncbi.nlm.nih.gov/pubmed/7685615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968530/
https://www.ncbi.nlm.nih.gov/pubmed/7685615

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