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Pharmacology and antitumour effects of intraportal pirarubicin on experimental liver metastases.

Early liver metastases have a predominant portal blood supply. Intraportal (i.port.) vein administration of cytotoxics could theoretically achieve enhanced drug concentrations in tumour cells and be effective as adjuvant therapy after resection of colorectal carcinoma. Pirarubicin (which has a highe...

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Detalles Bibliográficos
Autores principales: Ramirez, L. H., Munck, J. N., Bognel, C., Zhao, Z., Ardouin, P., Poupon, M. F., Gouyette, A., Rougier, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968574/
https://www.ncbi.nlm.nih.gov/pubmed/8347482