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Pharmacology and antitumour effects of intraportal pirarubicin on experimental liver metastases.
Early liver metastases have a predominant portal blood supply. Intraportal (i.port.) vein administration of cytotoxics could theoretically achieve enhanced drug concentrations in tumour cells and be effective as adjuvant therapy after resection of colorectal carcinoma. Pirarubicin (which has a highe...
Autores principales: | Ramirez, L. H., Munck, J. N., Bognel, C., Zhao, Z., Ardouin, P., Poupon, M. F., Gouyette, A., Rougier, P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968574/ https://www.ncbi.nlm.nih.gov/pubmed/8347482 |
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