Decreased melphalan accumulation in a human breast cancer cell line selected for resistance to melphalan.

An in vitro model of acquired melphalan resistance was developed by serial incubation of an MCF-7 human breast cancer cell line in increasing concentrations of melphalan. The resulting derivative cell line, Me1R MCF-7, was 30-fold resistant to melphalan. Uptake studies demonstrated decreased initial...

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Detalles Bibliográficos
Autores principales: Moscow, J. A., Swanson, C. A., Cowan, K. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968594/
https://www.ncbi.nlm.nih.gov/pubmed/8398701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968594/
https://www.ncbi.nlm.nih.gov/pubmed/8398701

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