Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype.
Kaposi's sarcoma is a rare neoplasm of characteristic chronicity. The classical form which occurs most often in elderly men of Eastern European origin, comprises both an indolent, cutaneous type marked by spontaneous regression with prolonged survival, and a rarer, disseminated variant is more...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968596/ https://www.ncbi.nlm.nih.gov/pubmed/8398706 |
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author | Ron, I. G. Kuten, A. Wigler, N. Fried, G. Nitezky, S. Inbar, M. J. Dale, J. Chaitchik, S. |
author_facet | Ron, I. G. Kuten, A. Wigler, N. Fried, G. Nitezky, S. Inbar, M. J. Dale, J. Chaitchik, S. |
author_sort | Ron, I. G. |
collection | PubMed |
description | Kaposi's sarcoma is a rare neoplasm of characteristic chronicity. The classical form which occurs most often in elderly men of Eastern European origin, comprises both an indolent, cutaneous type marked by spontaneous regression with prolonged survival, and a rarer, disseminated variant is more fulminant. Seven elderly Jewish patients with classical, disseminated, visceral Kaposi's sarcoma were studied; they were neither homosexual nor drug-abusers. All immunologic parameters were normal and serum tests for HIV antibodies, CMV, and EBV were negative. Five of these patients were treated and four responded well, including two complete remissions. The prolonged survival of these patients (82% at 5 years) suggests the existence of an indolent subtype or forme fruste of the usually aggressive form of classical Kaposi's sarcoma. |
format | Text |
id | pubmed-1968596 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1993 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-19685962009-09-10 Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. Ron, I. G. Kuten, A. Wigler, N. Fried, G. Nitezky, S. Inbar, M. J. Dale, J. Chaitchik, S. Br J Cancer Research Article Kaposi's sarcoma is a rare neoplasm of characteristic chronicity. The classical form which occurs most often in elderly men of Eastern European origin, comprises both an indolent, cutaneous type marked by spontaneous regression with prolonged survival, and a rarer, disseminated variant is more fulminant. Seven elderly Jewish patients with classical, disseminated, visceral Kaposi's sarcoma were studied; they were neither homosexual nor drug-abusers. All immunologic parameters were normal and serum tests for HIV antibodies, CMV, and EBV were negative. Five of these patients were treated and four responded well, including two complete remissions. The prolonged survival of these patients (82% at 5 years) suggests the existence of an indolent subtype or forme fruste of the usually aggressive form of classical Kaposi's sarcoma. Nature Publishing Group 1993-10 /pmc/articles/PMC1968596/ /pubmed/8398706 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Ron, I. G. Kuten, A. Wigler, N. Fried, G. Nitezky, S. Inbar, M. J. Dale, J. Chaitchik, S. Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title | Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title_full | Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title_fullStr | Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title_full_unstemmed | Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title_short | Classical disseminated Kaposi's sarcoma in HIV-negative patients; an unusually indolent subtype. |
title_sort | classical disseminated kaposi's sarcoma in hiv-negative patients; an unusually indolent subtype. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968596/ https://www.ncbi.nlm.nih.gov/pubmed/8398706 |
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