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The effect of MDR-1 gene expression on outcome in acute myeloblastic leukaemia.

Resistance to cytotoxic agents may be encountered during the treatment of acute myeloblastic leukaemia (AML). P-glycoprotein encoded by the MDR-1 gene has been implicated as a potential drug resistance mechanism in leukaemic cells. In recent years, many data have been accrued concerning the expressi...

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Detalles Bibliográficos
Autores principales: Holmes, J. A., West, R. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968682/
https://www.ncbi.nlm.nih.gov/pubmed/7905280