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Biological effects of stable overexpression of aromatase in human hormone-dependent breast cancer cells.

Aromatase is a key enzyme in the conversion of androstenedione and testosterone to oestrone and oestradiol. Intratumoral aromatase activity is expressed by around 70% of breast carcinomas, but it is not clear what effect this has on the tumour phenotype. To address this question we expressed human a...

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Detalles Bibliográficos
Autores principales: Macaulay, V. M., Nicholls, J. E., Gledhill, J., Rowlands, M. G., Dowsett, M., Ashworth, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968759/
https://www.ncbi.nlm.nih.gov/pubmed/8286214