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Immunotoxins recognising a new epitope on the neural cell adhesion molecule have potent cytotoxic effects against small cell lung cancer.

The present study describes a comparison of two potent immunotoxins which utilise an identical targeting component, a monoclonal antibody (SEN7) specific for small cell lung cancer (SCLC), conjugated to two different effector components, blocked ricin (bR) and Pseudomonas exotoxin A (PE). SEN7 recog...

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Detalles Bibliográficos
Autores principales: Zangemeister-Wittke, U., Collinson, A. R., Frösch, B., Waibel, R., Schenker, T., Stahel, R. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968769/
https://www.ncbi.nlm.nih.gov/pubmed/7506925