Allelic loss on distal chromosome 17p is associated with poor prognosis in a group of Brazilian breast cancer patients.

We examined loss of heterozygosity (LOH) for two loci on chromosome 17p (D17S5 and TP53), and erbB-2 gene amplification, in primary breast cancers from 67 Brazilian patients. We identified two distinct regions of LOH on chromosome 17p, one spanning TP53 and the other a more telomeric region (D17S5)....

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Detalles Bibliográficos
Autores principales: Nagai, M. A., Pacheco, M. M., Brentani, M. M., Marques, L. A., Brentani, R. R., Ponder, B. A., Mulligan, L. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968822/
https://www.ncbi.nlm.nih.gov/pubmed/7908218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968822/
https://www.ncbi.nlm.nih.gov/pubmed/7908218

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