Cargando…
Allelic loss on distal chromosome 17p is associated with poor prognosis in a group of Brazilian breast cancer patients.
We examined loss of heterozygosity (LOH) for two loci on chromosome 17p (D17S5 and TP53), and erbB-2 gene amplification, in primary breast cancers from 67 Brazilian patients. We identified two distinct regions of LOH on chromosome 17p, one spanning TP53 and the other a more telomeric region (D17S5)....
Autores principales: | Nagai, M. A., Pacheco, M. M., Brentani, M. M., Marques, L. A., Brentani, R. R., Ponder, B. A., Mulligan, L. M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1994
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968822/ https://www.ncbi.nlm.nih.gov/pubmed/7908218 |
Ejemplares similares
-
Allelic imbalance at chromosome 17p13.3 (YNZ22) in breast cancer is independent of p53 mutation or p53 overexpression and is associated with poor prognosis at medium-term follow-up.
por: Thompson, A. M., et al.
Publicado: (1998) -
Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ.
por: Munn, K. E., et al.
Publicado: (1996) -
Allele loss from large regions of chromosome 17 is common only in certain histological subtypes of ovarian carcinomas.
por: Papp, J., et al.
Publicado: (1996) -
Gain of Chromosome 20q Is an Indicator of Poor Prognosis in Colorectal Cancer
por: Postma, C., et al.
Publicado: (2007) -
p53 gene mRNA expression and chromosome 17p allele loss in breast cancer.
por: Thompson, A. M., et al.
Publicado: (1990)