Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas.

In this study we have screened a series of 29 primary leiomyosarcomas for abnormalities of both the p53 gene and the MDM2 gene, which encodes a p53-associated protein. SSCP (single-strand conformation polymorphism) analysis and direct sequencing of polymerase chain reaction (PCR)-amplified DNA were...

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Detalles Bibliográficos
Autores principales: Patterson, H., Gill, S., Fisher, C., Law, M. G., Jayatilake, H., Fletcher, C. D., Thomas, M., Grimer, R., Gusterson, B. A., Cooper, C. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1969417/
https://www.ncbi.nlm.nih.gov/pubmed/8198970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1969417/
https://www.ncbi.nlm.nih.gov/pubmed/8198970

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