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The Inheritance of Resistance Alleles in Multiple Sclerosis

Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. HLA-DRB1*15 and HLA-DRB1*17-bearing haplotypes and interactions at the HLA-DRB1 locus increase risk of MS but it has taken large samples to identif...

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Detalles Bibliográficos
Autores principales: Ramagopalan, Sreeram V, Morris, Andrew P, Dyment, David A, Herrera, Blanca M, DeLuca, Gabriele C, Lincoln, Matthew R, Orton, Sarah M, Chao, Michael J, Sadovnick, A. Dessa, Ebers, George C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971120/
https://www.ncbi.nlm.nih.gov/pubmed/17845076
http://dx.doi.org/10.1371/journal.pgen.0030150