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Orthologous Transcription Factors in Bacteria Have Different Functions and Regulate Different Genes

Transcription factors (TFs) form large paralogous gene families and have complex evolutionary histories. Here, we ask whether putative orthologs of TFs, from bidirectional best BLAST hits (BBHs), are evolutionary orthologs with conserved functions. We show that BBHs of TFs from distantly related bac...

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Detalles Bibliográficos
Autores principales: Price, Morgan N, Dehal, Paramvir S, Arkin, Adam P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971122/
https://www.ncbi.nlm.nih.gov/pubmed/17845071
http://dx.doi.org/10.1371/journal.pcbi.0030175