A bispecific monoclonal antibody against methotrexate and a human tumour associated antigen augments cytotoxicity of methotrexate-carrier conjugate.

A bispecific monoclonal antibody, reactive with methotrexate (MTX) and a tumour associated antigen (gp72) has been produced by fusing spleen cells from MTX immunised mice with 791T/36/3 (anti-gp72) hybridoma. The hybrid antibody was purified from anti-MTX and anti-gp72 antibodies present in the hybr...

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Detalles Bibliográficos
Autores principales: Pimm, M. V., Robins, R. A., Embleton, M. J., Jacobs, E., Markham, A. J., Charleston, A., Baldwin, R. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971384/
https://www.ncbi.nlm.nih.gov/pubmed/2331436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971384/
https://www.ncbi.nlm.nih.gov/pubmed/2331436

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