DNA damage and sequence specificity of DNA binding of the new anti-cancer agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate)

The DNA damage and the sequence specificity of guanine-N7 alkylation produced by the novel, positively charged, antineoplastic agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate) and its uncharged tertiary amine analogue 1,4-bis(2'-chloroethyl)-1,4-diaz...

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Detalles Bibliográficos
Autores principales: Broggini, M., Hartley, J. A., Mattes, W. B., Ponti, M., Kohn, K. W., D'Incalci, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971404/
https://www.ncbi.nlm.nih.gov/pubmed/2393411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971404/
https://www.ncbi.nlm.nih.gov/pubmed/2393411

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