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Enhancement of chemotherapy and nitroimidazole-induced chemopotentiation by the vasoactive agent hydralazine.
Nitroimidazoles have been shown to be potent sensitisers of certain clinically active chemotherapeutic agents. This process of chemopotentiation has been shown to be hypoxia-mediated. The present studies evaluated whether increasing the level of hypoxia in the tumour tissue, by treatment with the va...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971466/ https://www.ncbi.nlm.nih.gov/pubmed/2206941 |