Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis.

c-erbB-2 gene amplification and protein over-expression were investigated in 89 primary tumours and 24 metastases from Norwegian breast cancer patients. Amplification occurred in 22.5% of the primary tumours and 50% of the metastases. The amplification was negatively correlated to the oestrogen rece...

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Detalles Bibliográficos
Autores principales: Børresen, A. L., Ottestad, L., Gaustad, A., Andersen, T. I., Heikkilä, R., Jahnsen, T., Tveit, K. M., Nesland, J. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971471/
https://www.ncbi.nlm.nih.gov/pubmed/1977466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971471/
https://www.ncbi.nlm.nih.gov/pubmed/1977466

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