Reversal of acquired resistance to adriamycin in CHO cells by tamoxifen and 4-hydroxy tamoxifen: role of drug interaction with alpha 1 acid glycoprotein.

Tamoxifen and 4-OH tamoxifen were used to reverse multidrug resistance (MDR) in CHO cells with acquired resistance to adriamycin (CHO-Adrr). Because alpha 1 acid glycoprotein (AAG) can bind a range of calcium channel blockers that also reverse MDR and rises in malignancy, its interactions with tamox...

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Detalles Bibliográficos
Autores principales: Chatterjee, M., Harris, A. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971515/
https://www.ncbi.nlm.nih.gov/pubmed/2245162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971515/
https://www.ncbi.nlm.nih.gov/pubmed/2245162

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