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Ploidy as a prognostic indicator in end stage squamous cell carcinoma of the head and neck region treated with cisplatinum.

We measured tumour cellular DNA in 102 patients entered into two phase III trials of chemotherapy for end stage squamous carcinoma of the head and neck. The median survival of untreated patients with aneuploid tumours was 55 days compared with 224 days for patients treated with cisplatinum. This dif...

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Detalles Bibliográficos
Autores principales: Cooke, L. D., Cooke, T. G., Bootz, F., Forster, G., Helliwell, T. R., Spiller, D., Stell, P. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971589/
https://www.ncbi.nlm.nih.gov/pubmed/2337512