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The effect of an anti-membrane antibody-methotrexate conjugate on the human prostatic tumour line PC3.

Methotrexate (MTX) was linked, via an active ester intermediate, to a purified IgG fraction of rabbit polyclonal antiserum raised against a cell membrane preparation from the human prostatic cell line PC3. The resulting conjugates contained an average of 0.044 mg of MTX per mg of antibody with accep...

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Detalles Bibliográficos
Autores principales: Rowland, A. J., Harper, M. E., Wilson, D. W., Griffiths, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971590/
https://www.ncbi.nlm.nih.gov/pubmed/2337507