Cargando…
The effect of an anti-membrane antibody-methotrexate conjugate on the human prostatic tumour line PC3.
Methotrexate (MTX) was linked, via an active ester intermediate, to a purified IgG fraction of rabbit polyclonal antiserum raised against a cell membrane preparation from the human prostatic cell line PC3. The resulting conjugates contained an average of 0.044 mg of MTX per mg of antibody with accep...
Autores principales: | Rowland, A. J., Harper, M. E., Wilson, D. W., Griffiths, K. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1990
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971590/ https://www.ncbi.nlm.nih.gov/pubmed/2337507 |
Ejemplares similares
-
A bispecific monoclonal antibody against methotrexate and a human tumour associated antigen augments cytotoxicity of methotrexate-carrier conjugate.
por: Pimm, M. V., et al.
Publicado: (1990) -
Monoclonal antibody targeting of methotrexate (MTX) against MTX-resistant tumour cell lines.
por: Affleck, K., et al.
Publicado: (1992) -
Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate.
por: Embleton, M. J., et al.
Publicado: (1983) -
Co-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application
por: Moura, Catarina Costa, et al.
Publicado: (2014) -
Mathematical and experimental analysis of localization of anti-tumour antibody–enzyme conjugates
por: Jackson, T L, et al.
Publicado: (1999)