Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer.

Inherited susceptibility to a wide variety of neoplasias (Li-Fraumeni syndrome), has been shown in studies of one cancer-prone family, to have an intriguing association with an aberrant c-raf-1 gene and inheritance of a radioresistant phenotype in their non-cancerous skin fibroblasts. This associati...

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Detalles Bibliográficos
Autores principales: Cunningham, J. M., Francis, G. E., Holland, M. J., Pirollo, K. F., Chang, E. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971654/
https://www.ncbi.nlm.nih.gov/pubmed/1846552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971654/
https://www.ncbi.nlm.nih.gov/pubmed/1846552

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