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The effect of hyperthermia in combination with melphalan on drug-sensitive and drug-resistant CHO cells in vitro.
The effect of temperature on the cytotoxicity of melphalan in a pleiotropic drug-resistant mutant CHO cell line (CHR C5) and in its drug-sensitive parent (Aux B1) was studied in vitro using a clonogenic assay. The cytotoxicity of melphalan was significantly enhanced at elevated but non-lethal temper...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971810/ https://www.ncbi.nlm.nih.gov/pubmed/1974814 |