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Distribution of tamoxifen and metabolites into brain tissue and brain metastases in breast cancer patients.

We determined the amount of tamoxifen, N-desmethyltamoxifen (metabolite X), N-desdimethyltamoxifen (metabolite Z), and hydroxylated metabolites (Y, B, BX) in brain metastases from breast cancer and in the surrounding brain tissues. Specimens were collected from the breast cancer patients who receive...

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Detalles Bibliográficos
Autores principales: Lien, E. A., Wester, K., Lønning, P. E., Solheim, E., Ueland, P. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972343/
https://www.ncbi.nlm.nih.gov/pubmed/2021551