Pharmacokinetics and cytotoxicity of RSU-1069 in subcutaneous 9L tumours under oxic and hypoxic conditions.

The acute toxicity, pharmacokinetics and hypoxic cytotoxicity of RSU-1069 were investigated using the subcutaneous (sc) rat 9L tumour model. The pharmacokinetics were studied after i.p. injection of RSU-1069 (20 mg kg-1 or 100 mg kg-1). For both doses, the elimination of RSU-1069 followed first-orde...

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Detalles Bibliográficos
Autores principales: Wong, K. H., Koch, C. J., Wallen, C. A., Wheeler, K. T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972348/
https://www.ncbi.nlm.nih.gov/pubmed/2021530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972348/
https://www.ncbi.nlm.nih.gov/pubmed/2021530

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