High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India.

57 primary tumour samples from Indian oral cancer patients with a 5-15 year tobacco chewing habit, were examined for mutational activation in codons 12, 13 and 61 of the H-ras, K-ras and N-ras oncogenes. The highly sensitive assay based on specific oligonucleotide hybridisation following in vitro am...

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Detalles Bibliográficos
Autores principales: Saranath, D., Chang, S. E., Bhoite, L. T., Panchal, R. G., Kerr, I. B., Mehta, A. R., Johnson, N. W., Deo, M. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972357/
https://www.ncbi.nlm.nih.gov/pubmed/2021541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972357/
https://www.ncbi.nlm.nih.gov/pubmed/2021541

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