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Multiple sequential molecular abnormalities in the evolution of human gliomas.

We have examined a series of 13 benign and 27 malignant human gliomas for evidence of molecular abnormalities of proto-oncogene and putative tumour suppressor gene loci. The results indicated that specific molecular lesions were associated with increasing grades of malignancy. Thus, loss of genetic...

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Detalles Bibliográficos
Autores principales: Venter, D. J., Thomas, D. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972386/
https://www.ncbi.nlm.nih.gov/pubmed/1674878