N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymers containing doxorubicin (DOX) and galactosamine can be targeted to the hepatocyte galactose receptor for organ-specific chemotherapy of primary and metastatic liver cancer. Here we report the dose-dependent pharmacokinetics of this macromolecular co...

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Detalles Bibliográficos
Autores principales: Seymour, L. W., Ulbrich, K., Wedge, S. R., Hume, I. C., Strohalm, J., Duncan, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972557/
https://www.ncbi.nlm.nih.gov/pubmed/1648946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972557/
https://www.ncbi.nlm.nih.gov/pubmed/1648946

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