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Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi

The retinoblastoma (RB)/p16(INK4a) pathway regulates senescence of human melanocytes in culture and oncogene-induced senescence of melanocytic nevi in vivo. This senescence response is likely due to chromatin modifications because RB complexes from senescent melanocytes contain increased levels of h...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Debdutta, Curry, Jonathan L, Lin, Qiushi, Richards, Hunter W, Chen, Dahu, Hornsby, Peter J, Timchenko, Nikolai A, Medrano, Estela E
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1974778/
https://www.ncbi.nlm.nih.gov/pubmed/17578512
http://dx.doi.org/10.1111/j.1474-9726.2007.00308.x