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Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy
AIMS/HYPOTHESIS: Type 1 diabetes results from the autoimmune destruction of pancreatic beta cells. Exogenous insulin therapy cannot achieve precise physiological control of blood glucose concentrations, and debilitating complications develop. Lentiviral vectors are promising tools for liver-directed...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1975734/ https://www.ncbi.nlm.nih.gov/pubmed/17598085 http://dx.doi.org/10.1007/s00125-007-0722-0 |