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Effective killing of the human pathogen Candida albicans by a specific inhibitor of non-essential mitotic kinesin Kip1p

Kinesins from the bipolar (Kinesin-5) family are conserved in eukaryotic organisms and play critical roles during the earliest stages of mitosis to mediate spindle pole body separation and formation of a bipolar mitotic spindle. To date, genes encoding bipolar kinesins have been reported to be essen...

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Detalles Bibliográficos
Autores principales: Chua, Penelope R, Roof, David M, Lee, Yan, Sakowicz, Roman, Clarke, David, Pierce, Dan, Stephens, Thoryn, Hamilton, Matthew, Morgan, Brad, Morgans, David, Nakai, Takashi, Tomasi, Adam, Maxon, Mary E
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976386/
https://www.ncbi.nlm.nih.gov/pubmed/17573815
http://dx.doi.org/10.1111/j.1365-2958.2007.05787.x