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Effective killing of the human pathogen Candida albicans by a specific inhibitor of non-essential mitotic kinesin Kip1p
Kinesins from the bipolar (Kinesin-5) family are conserved in eukaryotic organisms and play critical roles during the earliest stages of mitosis to mediate spindle pole body separation and formation of a bipolar mitotic spindle. To date, genes encoding bipolar kinesins have been reported to be essen...
Autores principales: | Chua, Penelope R, Roof, David M, Lee, Yan, Sakowicz, Roman, Clarke, David, Pierce, Dan, Stephens, Thoryn, Hamilton, Matthew, Morgan, Brad, Morgans, David, Nakai, Takashi, Tomasi, Adam, Maxon, Mary E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976386/ https://www.ncbi.nlm.nih.gov/pubmed/17573815 http://dx.doi.org/10.1111/j.1365-2958.2007.05787.x |
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