Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population

BACKGROUND: The protein tyrosine phosphatase N22 gene (PTPN22) encodes a lymphoid-specific phosphatase (LYP) which is an important downregulator of T cell activation. A PTPN22 polymorphism, C1858T, was found associated with type 1 diabetes (T1D) in different Caucasian populations. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Santiago, Jose Luis, Martínez, Alfonso, de la Calle, Hermenegildo, Fernández-Arquero, Miguel, Figueredo, M Ángeles, de la Concha, Emilio G, Urcelay, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976418/
https://www.ncbi.nlm.nih.gov/pubmed/17697317
http://dx.doi.org/10.1186/1471-2350-8-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976418/
https://www.ncbi.nlm.nih.gov/pubmed/17697317
http://dx.doi.org/10.1186/1471-2350-8-54

Ejemplares similares