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Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain
Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for proteins involved in purine metabolism by directly sensing intracellular adenine levels. Adenine binds with high affinity and specificity to...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976443/ https://www.ncbi.nlm.nih.gov/pubmed/17686787 http://dx.doi.org/10.1093/nar/gkm565 |