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Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K(+) solution: insights into structure polymorphism of the human telomeric sequence
Formation of the G-quadruplex in the human telomeric sequence can inhibit the activity of telomerase, thus the intramolecular telomeric G-quadruplexes have been considered as an attractive anticancer target. Information of intramolecular telomeric G-quadruplex structures formed under physiological c...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976458/ https://www.ncbi.nlm.nih.gov/pubmed/17626043 http://dx.doi.org/10.1093/nar/gkm522 |