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Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K(+) solution: insights into structure polymorphism of the human telomeric sequence

Formation of the G-quadruplex in the human telomeric sequence can inhibit the activity of telomerase, thus the intramolecular telomeric G-quadruplexes have been considered as an attractive anticancer target. Information of intramolecular telomeric G-quadruplex structures formed under physiological c...

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Detalles Bibliográficos
Autores principales: Dai, Jixun, Carver, Megan, Punchihewa, Chandanamali, Jones, Roger A., Yang, Danzhou
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976458/
https://www.ncbi.nlm.nih.gov/pubmed/17626043
http://dx.doi.org/10.1093/nar/gkm522