Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells

The induction of interferon beta (IFNB1) is a key event in the antiviral immune response. We studied the role of transcriptional noise in the regulation of the IFNB1 locus in primary cultures of human dendritic cells (DCs), which are important ‘first responders’ to viral infection. In single cell as...

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Detalles Bibliográficos
Autores principales: Hu, Jianzhong, Sealfon, Stuart C., Hayot, Fernand, Jayaprakash, Ciriyam, Kumar, Madhu, Pendleton, Audrey C., Ganee, Arnaud, Fernandez-Sesma, Ana, Moran, Thomas M., Wetmur, James G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976463/
https://www.ncbi.nlm.nih.gov/pubmed/17675303
http://dx.doi.org/10.1093/nar/gkm557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976463/
https://www.ncbi.nlm.nih.gov/pubmed/17675303
http://dx.doi.org/10.1093/nar/gkm557

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