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Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells
The induction of interferon beta (IFNB1) is a key event in the antiviral immune response. We studied the role of transcriptional noise in the regulation of the IFNB1 locus in primary cultures of human dendritic cells (DCs), which are important ‘first responders’ to viral infection. In single cell as...
Autores principales: | Hu, Jianzhong, Sealfon, Stuart C., Hayot, Fernand, Jayaprakash, Ciriyam, Kumar, Madhu, Pendleton, Audrey C., Ganee, Arnaud, Fernandez-Sesma, Ana, Moran, Thomas M., Wetmur, James G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976463/ https://www.ncbi.nlm.nih.gov/pubmed/17675303 http://dx.doi.org/10.1093/nar/gkm557 |
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