Detection of phosphodiester adducts formed by the reaction of benzo[a]pyrene diol epoxide with 2′-deoxynucleotides using collision-induced dissociation electrospray ionization tandem mass spectrometry

In this study, we investigated the products formed following the reaction of benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (B[a]PDE) with 2′-deoxynucleoside 3′-monophosphates. The B[a]PDE plus 2′-deoxynucleotide reaction mixtures were purified using solid phase extraction (SPE) and subjected to HPLC w...

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Detalles Bibliográficos
Autores principales: Gaskell, Margaret, Kaur, Balvinder, Farmer, Peter B., Singh, Rajinder
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976470/
https://www.ncbi.nlm.nih.gov/pubmed/17636312
http://dx.doi.org/10.1093/nar/gkm526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976470/
https://www.ncbi.nlm.nih.gov/pubmed/17636312
http://dx.doi.org/10.1093/nar/gkm526

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