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The Cyclic AMP Cascade Is Altered in the Fragile X Nervous System

Fragile X syndrome (FX), the most common heritable cause of mental retardation and autism, is a developmental disorder characterized by physical, cognitive, and behavioral deficits. FX results from a trinucleotide expansion mutation in the fmr1 gene that reduces levels of fragile X mental retardatio...

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Detalles Bibliográficos
Autores principales: Kelley, Daniel J., Davidson, Richard J., Elliott, Jamie L., Lahvis, Garet P., Yin, Jerry C. P., Bhattacharyya, Anita
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976557/
https://www.ncbi.nlm.nih.gov/pubmed/17895972
http://dx.doi.org/10.1371/journal.pone.0000931