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Transcriptional Program Induced by Wnt Protein in Human Fibroblasts Suggests Mechanisms for Cell Cooperativity in Defining Tissue Microenvironments

BACKGROUND: The Wnt signaling system plays key roles in development, regulation of stem cell self-renewal and differentiation, cell polarity, morphogenesis and cancer. Given the multifaceted roles of Wnt signaling in these processes, its transcriptional effects on the stromal cells that make up the...

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Detalles Bibliográficos
Autores principales: Klapholz-Brown, Zach, Walmsley, Graham G., Nusse, Ysbrand M., Nusse, Roel, Brown, Patrick O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976560/
https://www.ncbi.nlm.nih.gov/pubmed/17895986
http://dx.doi.org/10.1371/journal.pone.0000945