Endocytosis of DNA-Hsp65 Alters the pH of the Late Endosome/Lysosome and Interferes with Antigen Presentation

BACKGROUND: Experimental models using DNA vaccine has shown that this vaccine is efficient in generating humoral and cellular immune responses to a wide variety of DNA-derived antigens. Despite the progress in DNA vaccine development, the intracellular transport and fate of naked plasmid DNA in euka...

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Detalles Bibliográficos
Autores principales: Trombone, Ana Paula F., Silva, Célio L., Lima, Karla M., Oliver, Constance, Jamur, Maria Célia, Prescott, Alan R., Coelho-Castelo, Arlete A. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976595/
https://www.ncbi.nlm.nih.gov/pubmed/17895965
http://dx.doi.org/10.1371/journal.pone.0000923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976595/
https://www.ncbi.nlm.nih.gov/pubmed/17895965
http://dx.doi.org/10.1371/journal.pone.0000923

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