Cargando…

Endocytosis of DNA-Hsp65 Alters the pH of the Late Endosome/Lysosome and Interferes with Antigen Presentation

BACKGROUND: Experimental models using DNA vaccine has shown that this vaccine is efficient in generating humoral and cellular immune responses to a wide variety of DNA-derived antigens. Despite the progress in DNA vaccine development, the intracellular transport and fate of naked plasmid DNA in euka...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trombone, Ana Paula F., Silva, Célio L., Lima, Karla M., Oliver, Constance, Jamur, Maria Célia, Prescott, Alan R., Coelho-Castelo, Arlete A. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976595/ https://www.ncbi.nlm.nih.gov/pubmed/17895965 http://dx.doi.org/10.1371/journal.pone.0000923

Ejemplares similares

Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells
por: Trombone, Ana Paula F, et al.
Publicado: (2007)

A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells
por: Franco, Luís H, et al.
Publicado: (2008)

DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
por: Santos, Rubens R, et al.
Publicado: (2009)

Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes
por: Rosada, Rogério S, et al.
Publicado: (2008)

Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery
por: Coelho-Castelo, AAM, et al.
Publicado: (2006)

Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage
por: Pelizon, Ana Cláudia, et al.
Publicado: (2007)

Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content
por: Mundy, Dorothy I., et al.
Publicado: (2012)

Antigen-presenting cells transfected with Hsp65 messenger RNA fail to treat experimental tuberculosis
por: Rocha, C.D., et al.
Publicado: (2012)

Endosomal/lysosomal location of organically modified silica nanoparticles following caveolae-mediated endocytosis
por: Wu, Changyue, et al.
Publicado: (2019)

Intracellular Trafficking Pathways of Edwardsiella tarda: From Clathrin- and Caveolin-Mediated Endocytosis to Endosome and Lysosome
por: Sui, Zhi-hai, et al.
Publicado: (2017)

B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
por: Fontoura, I. C., et al.
Publicado: (2015)

Immunotherapeutic Activities of a DNA Plasmid Carrying the Mycobacterial hsp65 Gene (DNAhsp65)
por: Silva, Celio Lopes, et al.
Publicado: (2020)

Administration of M. leprae Hsp65 Interferes with the Murine Lupus Progression
por: Marengo, Eliana B., et al.
Publicado: (2008)

Infectious bronchitis virus entry mainly depends on clathrin mediated endocytosis and requires classical endosomal/lysosomal system
por: Wang, Huan, et al.
Publicado: (2019)

Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes
por: Lund, Viktor Karlovich, et al.
Publicado: (2018)

Endocytosis and early endosome motility in filamentous fungi
por: Steinberg, Gero
Publicado: (2014)

Serotonin: an overlooked regulator of endocytosis and endosomal sorting?
por: Redpath, Gregory, et al.
Publicado: (2022)

Altered endosomal-lysosomal biogenesis in melanoma
por: Lam, Giang T., et al.
Publicado: (2023)

Oropouche virus entry into HeLa cells involves clathrin and requires endosomal acidification()
por: Santos, Rodrigo I.M., et al.
Publicado: (2008)

Endosomes and Golgi vesicles in adsorptive and fluid phase endocytosis
Publicado: (1984)

Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes
por: Joshi, Bhagyashree S., et al.
Publicado: (2020)

Glycans in autophagy, endocytosis and lysosomal functions
por: Reggiori, Fulvio, et al.
Publicado: (2021)

Recruitment of dynein to late endosomes and lysosomes through light intermediate chains
por: Tan, Serena C., et al.
Publicado: (2011)

Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump
Publicado: (1995)

B cells Can Modulate the CD8 Memory T Cell after DNA Vaccination Against Experimental Tuberculosis
por: Almeida, Luciana P, et al.
Publicado: (2011)

Translocation and clustering of endosomes and lysosomes depends on microtubules
Publicado: (1987)

LRRK2 at the interface of autophagosomes, endosomes and lysosomes
por: Roosen, Dorien A., et al.
Publicado: (2016)

Neuronal endosomes to lysosomes: A journey to the soma
por: Kulkarni, Vineet Vinay, et al.
Publicado: (2018)

Editorial: Signaling Proteins for Endosomal and Lysosomal Function
por: Capelluto, Daniel G. S., et al.
Publicado: (2021)

The Role of Intraorganellar Ca(2+)In Late Endosome–Lysosome Heterotypic Fusion and in the Reformation of Lysosomes from Hybrid Organelles
por: Pryor, Paul R., et al.
Publicado: (2000)

ER network homeostasis is critical for plant endosome streaming and endocytosis
por: Stefano, Giovanni, et al.
Publicado: (2015)

Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro
por: Rosazza, Christelle, et al.
Publicado: (2016)

An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes
Publicado: (1996)

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus
por: Kühnl, Alexander, et al.
Publicado: (2018)

The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments
por: Cortese, Katia, et al.
Publicado: (2013)

The morphology but not the function of endosomes and lysosomes is altered by brefeldin A
Publicado: (1992)

The endosome–lysosome pathway and information generation in the immune system()
por: Watts, Colin
Publicado: (2012)

Unconventional secretion of FABP4 by endosomes and secretory lysosomes
por: Villeneuve, Julien, et al.
Publicado: (2018)

Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes
por: Wong, Ching-On
Publicado: (2020)

Implications of Altered Endosome and Lysosome Biology in Space Environments
por: Johnson, Ian R. D., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cfv0jaecshq6g9o8jaauecu8o1