GSK-3 inhibitors induce chromosome instability

BACKGROUND: Several mechanisms operate during mitosis to ensure accurate chromosome segregation. However, during tumour evolution these mechanisms go awry resulting in chromosome instability. While several lines of evidence suggest that mutations in adenomatous polyposis coli (APC) may promote chrom...

Descripción completa

Detalles Bibliográficos
Autores principales: Tighe, Anthony, Ray-Sinha, Arpita, Staples, Oliver D, Taylor, Stephen S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976608/
https://www.ncbi.nlm.nih.gov/pubmed/17697341
http://dx.doi.org/10.1186/1471-2121-8-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976608/
https://www.ncbi.nlm.nih.gov/pubmed/17697341
http://dx.doi.org/10.1186/1471-2121-8-34

Ejemplares similares