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GSK-3 inhibitors induce chromosome instability
BACKGROUND: Several mechanisms operate during mitosis to ensure accurate chromosome segregation. However, during tumour evolution these mechanisms go awry resulting in chromosome instability. While several lines of evidence suggest that mutations in adenomatous polyposis coli (APC) may promote chrom...
Autores principales: | Tighe, Anthony, Ray-Sinha, Arpita, Staples, Oliver D, Taylor, Stephen S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976608/ https://www.ncbi.nlm.nih.gov/pubmed/17697341 http://dx.doi.org/10.1186/1471-2121-8-34 |
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