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Phosphorylation of Ser(78 )of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer

BACKGROUND: Abnormal amplification/expression of HER-2/neu oncogene has been causally linked with tumorigenesis and metastasis in breast cancer and associated with shortened overall survival of patients. Recently, heat shock protein 27 (Hsp27) was reported to be highly expressed in HER-2/neu positiv...

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Detalles Bibliográficos
Autores principales: Zhang, Daohai, Wong, Lee Lee, Koay, Evelyn SC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976621/
https://www.ncbi.nlm.nih.gov/pubmed/17697330
http://dx.doi.org/10.1186/1476-4598-6-52