Cargando…

Phosphorylation of Ser(78 )of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer

BACKGROUND: Abnormal amplification/expression of HER-2/neu oncogene has been causally linked with tumorigenesis and metastasis in breast cancer and associated with shortened overall survival of patients. Recently, heat shock protein 27 (Hsp27) was reported to be highly expressed in HER-2/neu positiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Daohai, Wong, Lee Lee, Koay, Evelyn SC
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976621/ https://www.ncbi.nlm.nih.gov/pubmed/17697330 http://dx.doi.org/10.1186/1476-4598-6-52

Ejemplares similares

Factors Influencing Lymph Node Positivity in HER2/neu+ Breast Cancer Patients
por: Englander, Katherine, et al.
Publicado: (2023)

Expression and prognostic value of HER-2/neu in primary breast cancer with sentinel lymph node metastasis
por: Tong, Zhen-Jun, et al.
Publicado: (2017)

Prognostic value HER-2/neu expression in T1 to T3 breast cancer with axillary lymph node metastasis
por: Maksimovic, S
Publicado: (2009)

Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance
por: Hwang, Soo-Yeon, et al.
Publicado: (2020)

Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia
por: Zahari, Muhammad Saddiq, et al.
Publicado: (2015)

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth
por: Ho, Kuen Yao, et al.
Publicado: (2013)

Breast Cancer and Her-2/Neu
por: Sherwood, Roy
Publicado: (2005)

A novel intronic circular RNA, circGNG7, inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82
por: Ju, Houyu, et al.
Publicado: (2021)

Anti-Her-2/neu antibody induces apoptosis in Her-2/neu overexpressing breast cancer cells independently from p53 status
por: Brodowicz, T, et al.
Publicado: (2001)

HER-2/neu diagnostics in breast cancer
por: Carney, Walter P, et al.
Publicado: (2007)

The Clinical Importance of the Heterogeneity of HER2 neu
por: Davila, Enrique, et al.
Publicado: (2010)

The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase
por: Cappello, Francesco, et al.
Publicado: (2005)

Trafficking of High Avidity HER-2/neu-Specific T Cells into HER-2/neu-Expressing Tumors after Depletion of Effector/Memory-Like Regulatory T Cells
por: Weiss, Vivian L., et al.
Publicado: (2012)

Monocyte Proteomics Reveals Involvement of Phosphorylated HSP27 in the Pathogenesis of Osteoporosis
por: Daswani, Bhavna, et al.
Publicado: (2015)

Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy
por: Rodrigues, Loreta M, et al.
Publicado: (2012)

Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma
por: Joo, Mee, et al.
Publicado: (2005)

HER 2/neu protein expression in colorectal cancer
por: Schuell, B, et al.
Publicado: (2006)

HER-2/neu Testing and Therapy in Gastroesophageal Adenocarcinoma
por: Moelans, Cathy B., et al.
Publicado: (2010)

Anti-HER2/Neu passive-aggressive immunotherapy
por: Mortenson, Eric D, et al.
Publicado: (2014)

HER2/neu testing in primary colorectal carcinoma
por: Ingold Heppner, B, et al.
Publicado: (2014)

Review of the Role of HER2/neu in Colorectal Carcinomas
por: Achalla, Lakshmi Sai Vijay, et al.
Publicado: (2022)

C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer
por: Schlotter, Claus M, et al.
Publicado: (2003)

Upregulation of sialidase NEU3 in head and neck squamous cell carcinoma associated with lymph node metastasis
por: Shiga, Kiyoto, et al.
Publicado: (2015)

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules
por: Kim, Jee Hye, et al.
Publicado: (2016)

Functional assay for HER-2/neu demonstrates active signalling in a minority of HER-2/neu-overexpressing invasive human breast tumours.
por: DiGiovanna, M. P., et al.
Publicado: (1996)

p185(HER‐2/neu) and p21(CIP1/WAF1) Expression in Primary Tumors and Lymph Node Metastases in Non‐small Cell Lung Cancer
por: Akita, Kenji, et al.
Publicado: (2002)

Interrelationships Between Ki67, HER2/neu, p53, ER, and PR Status and Their Associations With Tumor Grade and Lymph Node Involvement in Breast Carcinoma Subtypes: Retrospective-Observational Analytical Study
por: Shokouh, Taghipour Zahir, et al.
Publicado: (2015)

Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8(+) T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice
por: Chen, Y, et al.
Publicado: (2011)

Factor Xa Inhibitor Suppresses the Release of Phosphorylated HSP27 from Collagen-Stimulated Human Platelets: Inhibition of HSP27 Phosphorylation via p44/p42 MAP Kinase
por: Tsujimoto, Masanori, et al.
Publicado: (2016)

HSP27 phosphorylation inhibitor regulates Her2 expression in human breast cancer cell line SK-BR-3 with induced Herceptin resistance
por: Kim, Min Kyung, et al.
Publicado: (2014)

Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using (89)Zr-DFO-Trastuzumab
por: Holland, Jason P., et al.
Publicado: (2010)

Long-term prognostic significance of HER-2/neu in untreated node-negative breast cancer depends on the method of testing
por: Schmidt, Marcus, et al.
Publicado: (2005)

HER-2/neu oncogene: what does amplification mean?
por: Pavy, J. J., et al.
Publicado: (1993)

Serological Her2/neu-determination in patients receiving Herceptin(®)
por: Thomas, A, et al.
Publicado: (2001)

HER2/neu-directed therapy for biliary tract cancer
por: Javle, Milind, et al.
Publicado: (2015)

Expression of HER-2/neu in Oral Squamous Cell Carcinoma
por: Mirza, Sana, et al.
Publicado: (2020)

Expression of Septin 2 and Her2/neu in Colorectal Cancer
por: Hanbuli, Hala M. El, et al.
Publicado: (2021)

Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span
por: Provinciali, Mauro, et al.
Publicado: (2017)

Status of HER-2/neu receptors and Ki-67 in breast cancer of Indian women
por: Singhai, Rajeev, et al.
Publicado: (2011)

Expression and clinical significance of HSP27 and its phosphorylation in lower extremity arteriosclerosis obliterans
por: Bai, Junqing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vrfk7tc4olmv6jjcvoro0894qp